Dipyridamole enhances osteogenesis of three-dimensionally printed bioactive ceramic scaffolds in calvarial defects
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Abstract: Dipyridamole Enhances Osteogenesis of 3D-Printed Bioactive Ceramic Scaffolds in Calvarial Defects
METHODS: Custom 3DPBC scaffolds designed to present lattice-based porosity only towards the dural surface were either coated with collagen (control) or coated with collagen and immersed in a 100 μM concentration dipyridamole (DIPY) solution. Sheep (n=5) were subjected to 2 ipsilateral trephine-induced (11 mm diameter) calvarial defects. Either a control or a DIPY scaffold was placed in each def...
متن کاملAbstract 47. Dipyridamole-Containing 3D-Printed Bioactive Ceramic Scaffolds for the Treatment of Calvarial Defects: An Experimental Study in Sheep
T ueday, M arch 8, 2017 METHODS: One hundred fifty-eight patients with 277 expanded skin cases during 2010 to 2014 were reviewed and photograph-evaluated for the expanded skin texture and regenerative condition. Overall texture of the expanded skin flaps (Good, Fair, Poor) were evaluated and documented by senior attending surgeons. The occurrence of five indications of skin regeneration limitat...
متن کاملAbstract: Dipyridamole Releasing 3D Printed Bioactive Ceramic Scaffolds with Osseoconductive Geometries Promote Craniofacial Bone Regeneration
METHODS: Custom 3DPBC scaffolds designed to present lattice-based porosity only towards the dural surface were either coated with collagen (control) or coated with collagen and immersed in a 100 μM concentration dipyridamole (DIPY) solution. Sheep (n=5) were subjected to 2 ipsilateral trephine-induced (11 mm diameter) calvarial defects. Either a control or a DIPY scaffold was placed in each def...
متن کاملAbstract: 3D-Printed Bioactive Ceramic Scaffolds Demonstrate Intrinsic Osteogenic Properties in an Undisturbed Osseous Environment
METHODS: Fat was harvested by manual liposuction and processed by standard Coleman technique from 24 patients undergoing fat grafting to the forefoot as part of a randomized cross-over clinical trial. Ultrasound-assessed submetatarsal tissue thickness was obtained at baseline, 6mo, & 12mo visits. Processed lipoaspirate was returned to the lab for stromal vascular fraction (SVF) isolation, flow ...
متن کامل3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering.
Coronary heart disease (CHD) and myocardial infarction (MI) account for ≈1 in 7 deaths in the United States, with an estimated 750 000 incidences of MI in the United States each year. Although modern medical therapies have reduced the number of coronary heart disease–related deaths over the past 30 years, there is still much room for improvement in coronary heart disease and MI treatment. As ca...
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ژورنال
عنوان ژورنال: Journal of Cranio-Maxillofacial Surgery
سال: 2018
ISSN: 1010-5182
DOI: 10.1016/j.jcms.2017.11.011